Interleukin-8 as a mediator of sympathetic pain
نویسندگان
چکیده
منابع مشابه
The Value of Interleukin-8 and Interleukin-6 in Cervical Secretions as Predictors of Preterm Delivery
Background and Objective: Preterm birth occurs in 8% to 11% of all pregnancies and is responsible for 75% to 80% of all neonatal deaths. Cytokines may be involved in the etiology of preterm birth through their stimulation of prostaglandin synthesis. Cytokines may be released intocervicovaginal fluid during the breakdown of the chorio-decidual adhesion or from an inflammatory reactio...
متن کاملIdentification of interleukin-1 beta as a key mediator in the upregulation of Cav3.2–USP5 interactions in the pain pathway
Abstract We recently reported that nerve injury or peripheral inflammation triggers an upregulation of the deubiquitinase, USP5 in mouse dorsal root ganglion and spinal dorsal horn. This leads to dysregulated ubiquitination of Cav3.2 T-type calcium channels, thus increasing Cav3.2 channel plasma membrane expression and nociceptive signaling in the primary afferent pain pathway. This phenomenon ...
متن کاملthe value of interleukin-8 and interleukin-6 in cervical secretions as predictors of preterm delivery
background and objective: preterm birth occurs in 8% to 11% of all pregnancies and is responsible for 75% to 80% of all neonatal deaths. cytokines may be involved in the etiology of preterm birth through their stimulation of prostaglandin synthesis. cytokines may be released intocervicovaginal fluid during the breakdown of the chorio-decidual adhesion or from an inflammatory reaction in the sam...
متن کاملExperiments on Histamine as the Chemical Mediator for Cutaneous Pain
Experimental evidence shows that histamine is liberated when the upper layers of the skin are stimulated in the threshold range although no gross or microscopic evidence of tissue damage is demonstrable. A histamine-like substance is recoverable from the anterior chamber of the rabbit's eye on electrical stimulation of the cornea. This substance is liberated in direct proportion to the intensit...
متن کاملInterleukin 8 (IL-8) - a universal biomarker?
Many clinical conditions including various types of cancers are complex and generally require invasive, laborious, expensive and time-consuming investigations for their diagnosis, treatment and follow-up. There is therefore a general need for exploring non-invasive markers in clinical medicine. Interleukin 8 (IL-8) is currently being applied in various subspecialties of medicine either for the ...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1991
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1991.tb12502.x